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Mabwell (Shanghai) Bioscience Co. Ltd. A

Mabwell (Shanghai) Bioscience Co., Ltd. is a biopharmaceutical company that researches, develops, manufactures, and commercializes biological products for oncology, immunology, bone disorders, ophthalmology, hematology, and infectious diseases in China and internationally. Its marketed products include MAIWEIJIAN for giant cell tumor of bone, MALISHU for postmenopausal osteoporosis, MAILISHENG (albipagrastim alfa injection), and JUNMAIKANG (an autoimmune Adalimumab injection). The company's pipeline includes oncology candidates such as 9MW2821 (a Nectin-4 targeting drug in Phase III for cervical cancer), 7MW3711 (a B7-H3 targeting ADC for advanced malignant solid tumors), and 7MW4911 (an ADC targeting CDH17), as well as immunology candidates 9MW1911 (an anti-ST2 antibody in Phase I for COPD) and 9MW3811 (an anti-IL-11 antibody in Phase I). Additional pipeline programs include 1MW5011 (an oral tablet for osteoarthritis), ophthalmology candidates 9MW0813 (a recombinant VEGF receptor-antibody fusion protein for vascularization-related ocular diseases) and 9MW0211 (a recombinant anti-VEGF humanized monoclonal antibody injection in Phase III for neovascular eye diseases such as neovascular age-related macular degeneration), and hematology candidate 9MW3011 (a recombinant humanized anti-TMPRSS6 monoclonal antibody in Phase I for polycythemia vera and iron overload disorders including beta-thalassemia). Founded in 2017, the company is headquartered in Shanghai, China.

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China
Biotech & Genomic Medicine▼7

Maiwei Biotech's first-half revenue more than tripled, with a net loss of 522 million yuan

Maiwei Biotech disclosed its 2026 semi-annual report on the evening of August 30. First-half revenue was 313 million yuan, a sharp year-on-year increase of 209.04 percent, but net profit attributable to the parent remained at minus 522 million yuan, narrowing from a loss of 551 million yuan in the same period last year. Revenue growth came mainly from drug sales of 212 million yuan and technical service income of 99.8557 million yuan, including domestic drug sales of Junmaikang of 75.373 million yuan, as well as revenue recognized from the company's licensing agreements with Kalexo and DISC. The company's research and development investment reached as high as 431 million yuan, up 10.03 percent year on year, and persistently high R&D spending dragged on profitability. As of the report's disclosure date, the company had 15 key products in clinical research or on the market, and the Phase III clinical trial of its core pipeline asset 9MW2821 had completed enrollment, with an interim analysis planned for the second half of 2026. The company cautioned that it may have accumulated uncovered losses in the coming years and may be unable to pay cash dividends.
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Biotech & Genomic Medicine › Oncology Therapeutics Competition
688062.CG · Capital · Negative Net loss of 522 million yuan despite revenue tripling, with high R&D spending dragging profitability.
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China
Biotech & Genomic Medicine▲

Mabwell Biotech Secures Exclusive Greater China License for SST001 Program

Mabwell Biotech announced that it plans to sign a project license agreement with its associate company Sinusai, obtaining an exclusive license for the SST001 program in Greater China. The company will pay an upfront fee of 20 million yuan, milestone payments of up to 20 million yuan, and a royalty of 4.3 percent on net sales. SST001 is a PET tracer labeled with the radionuclide fluorine-18 that specifically targets the pathological protein alpha-synuclein. It is intended for use in combination with PET/CT for the auxiliary diagnosis and differential diagnosis of alpha-synucleinopathies such as Parkinson's disease and multiple system atrophy.
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Biotech & Genomic Medicine › Neuroscience & Neurodegenerative ▲Technology
688062.CG · Capital · Positive Mabwell secures exclusive Greater China license for the SST001 PET tracer program via a licensing deal with upfront, milestone, and royalty payments.
思努赛 · Capital · Positive Sinusai, as licensor, grants Mabwell the SST001 Greater China rights and receives a 20M yuan upfront fee, up to 20M yuan milestones, and 4.3% royalties.
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Biotech & Genomic Medicine▲2

Innovative drug valuations recover, Sci-Tech Innovation Board Medical ETF Huaxia rises nearly 1%

The Sci-Tech Innovation Board Medical ETF Huaxia rose 0.83%, heading for a sixth consecutive gain, with the latest price at 1.1 yuan. The Shanghai Sci-Tech Innovation Board Biomedical Index advanced 0.89%, with constituent Hotgen Biotech surging 10.60% and Mabwell Biotech climbing 9.42%. The National Medical Products Administration plans to include eligible cell and gene therapy drugs in a 30-day review channel for innovative drug clinical trial approvals, a policy that is catalyzing a valuation recovery for innovative drugs. The ETF has seen net inflows for six consecutive days, attracting a total of 61.04 million yuan.
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Biotech & Genomic Medicine › Gene & Cell Editing ▲Regulation
688062.CG · Regulation · Positive NMPA policy to fast-track cell and gene therapy drugs benefits Mabwell's pipeline
688068.CG · Regulation · Positive NMPA policy to fast-track cell and gene therapy drugs benefits Hotgen's pipeline
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Biotech & Genomic Medicine▲2

Shouyao Holdings hits 20 percent daily limit as innovative drug sector rallies

The innovative drug sector opened lower on July 6 before climbing higher in choppy trade. Shouyao Holdings surged by the 20 percent daily limit, Maiwei Bio and Shutaishen jumped over 10 percent, BeiGene rose more than 6 percent, and Asymchem and Hengrui Medicine gained over 4 percent. On the news front, the General Office of the National Medical Products Administration recently sought public comments on a draft notice regarding optimizing the review and approval of cell and gene therapy drugs. The draft mentions supporting clinically driven innovation in cell and gene therapy drug development, focusing on key areas such as malignant tumors and rare diseases, encouraging global simultaneous development, and including eligible cell and gene therapy drugs in a 30-day review and approval channel for innovative drug clinical trials. A research note from Orient Securities noted that Chinese companies have recently made gradual breakthroughs in frontier fields such as cell therapy and AI-driven drug discovery. Several innovative drug makers have seen their core products enter the harvest stage, while medical insurance access, commercial insurance coverage, and cost ratio optimization are jointly driving continuous profit improvement.
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Biotech & Genomic Medicine › Cell Therapy (CAR-T & beyond) ▲Regulation
Biotech & Genomic Medicine › Gene & Cell Editing ▲Regulation
Biotech & Genomic Medicine › AI Drug Discovery ▲Technology
688197.CG · Regulation · Positive Draft notice on cell and gene therapy drug review supports innovative drug sector; Shouyao surged 20% daily limit as a key beneficiary.
688062.CG · Regulation · Positive Draft notice on cell and gene therapy drug review supports innovative drug sector; Mabwell is an innovative drug maker mentioned as jumping over 10%.
600276.CG · Regulation · Positive Draft notice on cell and gene therapy drug review supports innovative drug sector, benefiting Hengrui as a major innovative drug maker.
688235.CG · Regulation · Positive Draft notice on cell and gene therapy drug review supports innovative drug sector; BeiGene rose over 6% as an innovative drug maker.
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