Dynavax Technologies Corporation is a commercial-stage biopharmaceutical company focused on developing and commercializing vaccines in the United States and internationally. Its product HEPLISAV-B is a hepatitis B vaccine for adults aged 18 and older, and its CpG 1018 adjuvant is used in HEPLISAV-B. The company also develops rF1V, a Phase 2 plague vaccine candidate, and Z-1018, a Phase 1/2 shingles vaccine candidate for adults aged 50 and older, as well as HEPLISAV-B for adults on hemodialysis. It sells to hospitals, clinics, public health clinics, prisons, the Department of Defense, the Department of Veterans Affairs, and retail pharmacies through wholesalers and specialty distributors, and has collaboration agreements with the U.S. Department of Defense, the Coalition for Epidemic Preparedness Innovations, Zhejiang Clover Biopharmaceuticals, Clover Biopharmaceuticals (Hong Kong), and Biological E. Limited. Formerly known as Double Helix Corporation, it changed its name to Dynavax Technologies Corporation in September 1996, was incorporated in 1996, and is headquartered in Emeryville, California.