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Aktis Oncology, Inc. Common stock

Aktis Oncology, Inc. is a clinical-stage oncology company focused on the research, development, and commercialization of targeted radiopharmaceuticals for solid tumors. Its lead candidate, [225Ac]Ac-AKY-1189, is a miniprotein radioconjugate in Phase 1b trials for Nectin-4 expressing solid tumors, including urothelial, breast, NSCLC, colorectal, and cervical cancers. Another candidate, [225Ac]Ac-AKY-2519, targets B7-H3 (CD276) expressing tumors such as prostate and lung cancers. The company has license and collaboration agreements with Protein Innovation, Inc., TRIUMF Innovations, Inc., and Eli Lilly. Formerly HotKnot Therapeutics, Inc., it changed its name to Aktis Oncology, Inc. in April 2020, was incorporated in 2020, and is headquartered in Boston, Massachusetts.

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Biotech & Genomic Medicine▲

Novartis, Lilly, Bristol Myers Eye Aktis Oncology Takeover

Aktis Oncology, a clinical-stage radiopharmaceutical company, is seen as a potential acquisition target for Novartis, Eli Lilly, and Bristol Myers Squibb due to its alpha-emitting cancer platform and upcoming trial data. Aktis retains full worldwide rights to its miniprotein radioconjugate platform, with $517.3 million in cash and preliminary data from its lead candidate AKY-1189 expected in the first quarter of 2027. Novartis, whose Pluvicto grew 43% in Q2 2026, and Eli Lilly, already a $60 million upfront partner, rank as the top two strategic acquirers. Analysts target $34.42 for AKTS while the 24/7 Wall St. base case reaches $42.16, but a failed readout would erase the takeout premium entirely.
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Biotech & Genomic Medicine › Oncology Therapeutics Competition
AKTS · Capital · Positive Potential acquisition target with high takeover premium
NOVN.SW · Capital · Positive Pluvicto growth and potential acquisition of Aktis
BMY · Capital · Neutral Mentioned as potential acquirer, but no direct impact on BMS
LLY · Capital · Neutral Mentioned as potential acquirer, but no direct impact on Lilly
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