Alector, Inc. is a clinical-stage biotechnology company that develops therapies to counteract the progression of neurodegeneration in the United States. Its pipeline includes Nivisnebart, an investigational human recombinant monoclonal antibody for prevalent neurodegenerative diseases; AL137, an anti-amyloid beta antibody in preclinical development for Alzheimer's disease; and AL050, a GCase enzyme replacement therapy in preclinical development for Parkinson's disease and Lewy body dementia in patients with GBA1 gene mutations. The company also develops preclinical and research candidates such as AL064, a tau siRNA for Alzheimer's disease and other tauopathies; ADP062-ABC, an alpha-synuclein siRNA for Parkinson's disease; and ADP065-ABC, an NLRP3 siRNA for neurodegenerative conditions. Alector has a strategic collaboration with GlaxoSmithKline plc for the development and commercialization of progranulin-elevating monoclonal antibodies, including Latozinemab and Nivisnebart. Founded in 2013, it is headquartered in South San Francisco, California.