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Vor Biopharma Inc

Vor Biopharma Inc. is a clinical-stage biopharmaceutical company focused on developing a novel therapy for autoimmune diseases. Its product, telitacicept, is a fusion protein being developed for generalized myasthenia gravis, systemic lupus erythematosus, rheumatoid arthritis, Sjögren's disease, and IgA nephropathy. The company has a license agreement with RemeGen Co., Ltd. for the exploitation, development, and commercialization of telitacicept and related products. Vor Biopharma was incorporated in 2015 and is headquartered in Boston, Massachusetts.

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Biotech & Genomic Medicine▲

Vor Biopharma's Telitacicept Shows Durable Responses in Phase 3 Myasthenia Gravis Analysis

Vor Biopharma reported a post hoc analysis from a China-based Phase 3 trial showing that telitacicept produced deep, durable clinical responses and was generally well tolerated over 48 weeks in adults with generalized myasthenia gravis. The analysis highlighted that most patients who reached minimal symptom expression maintained it and spent much of their remaining follow-up in this state. The new data reinforce the depth and durability of response but do not materially change the key near-term catalyst, the UPSTREAM global Phase 3 topline readout in 2027, or the central risk that global data might not match prior China experience. The results sit beside Vor's completion of enrollment in the global UPSTREAM Phase 3 gMG trial in early September 2026. Vor Biopharma's narrative projects $111.0 million revenue and $19.1 million earnings by 2029, implying an earnings decrease of $608.7 million from $627.8 million today, and forecasts a $39.00 fair value, a 109% upside to its current price.
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Biotech & Genomic Medicine › Autoimmune & Immunology Therapeutics Technology
VOR · Technology · Positive Post hoc Phase 3 analysis shows telitacicept produced deep, durable responses over 48 weeks in generalized myasthenia gravis, reinforcing the drug's clinical profile.
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